Jan 18 - International donors pledge US$1.9 billion to combat the spread of bird flu at a conference in Beijing.

Feb 8 - The first African cases of the deadly H5N1 strain are detected in poultry in the northern Nigerian states of Kano, Kaduna and Plateau.

Feb 11/12 - Italy says six wild swans found in Sicily and on the southern mainland tested positive for H5N1. In Greece, three swans found south of Thessaloniki test positive for H5N1. These are the first known cases of the strain in the EU. Several countries subsequently report outbreaks in wild birds.

Feb 17 - Egypt finds its first cases of H5N1 in chickens.

Feb 18 - India announces its first cases of H5N1, finding the virus in poultry in a western state.

Feb 22 - The EU approves plans by France and the Netherlands to vaccinate millions of hens, ducks and geese against bird flu.

Feb 25 - France confirms H5N1 at a farm in the east where thousands of turkeys have died. It is the first case of the virus in domestic farm birds in the EU.

May 11 - Djibouti announces its first case of human H5N1, in the first confirmed human case in the Horn of Africa.

July 26 - Pharmaceuticals group GlaxoSmithKline Plc says a bird flu vaccine for humans that uses only a very low dose of active ingredient has proved effective in clinical tests.

Aug 8 - China says its first H5N1 human case was in 2003, and not in 2005 as it had originally reported.