"My kids were very worried because the mother of one of their friends died," she added.

From Africa to Asia to Latin America, around 2.5 billion people live in areas that are at risk of dengue fever, a viral disease spread by the Aedes aegypti mosquito. There is no vaccine or drugs to treat the illness which killed an estimated 22,000 people last year, most of them children.

Due to international travel and climate change, the Aedes aegypti mosquito's habitat is spreading.

In January, health officials warned that the disease was poised to move across the United States. It has been spreading aggressively in Latin America and the Caribbean, reaching epidemic levels last year.

Dengue is endemic in Southeast Asia where a tropical climate and monsoon rains provide ideal conditions.

Strategies developed in places such as Singapore might provide vital information for other countries seeking to combat the virus and the mosquitoes that spread it. Family doctors in Singapore look out for patients with suspicious symptoms. When cases are confirmed, researchers try to nail down the specific dengue virus subtype, of which there are four, and the location of the outbreak.

"You need to monitor what (subtype) is going around ... You want to limit the damage, the fatalities," the World Health Organisation's advisor in Asia, John Ehrenberg, told Reuters.

While dengue and malaria share geographical patterns, dengue is more dangerous because its mosquito carriers thrive indoors. Mosquitoes that carry malaria are rarely found in urban areas.

Dengue fever is endemic in more than 100 countries in Africa, the Americas, eastern Mediterranean, Southeast Asia and western Pacific. Of the 50 million people who contract the disease every year, about one percent get potentially deadly severe dengue haemorrhagic fever (DHF), which requires hospitalisation.

There is no cure or vaccination for dengue fever. Sufferers such as Poon, face an increased likelihood of developing DHF if they contract the disease again, which is not uncommon for those living in the tropics where the mosquito carriers flourish.

NO STOPPING IT?

International travel has made the spread of dengue inevitable, experts say.

"There is always a risk for the borders ... In central America, you have a lot of people moving up north," Ehrenberg said. "There is a risk of people moving in with dengue."

Ehrenberg says there is little to stop dengue from spreading. He compares it to West Nile virus which appeared in New York in 1999 and then spread across the United States, Canada and Mexico. West Nile killed 98 people in the United States last year.

"As you can see with West Nile virus, there is hardly anything you can do to control its spread in the US It's all over the place now. There's always the risk of introducing, when the climatic conditions are right," Ehrenberg said.

Both dengue and West Nile are spread by mosquitoes.

"It's a neglected disease because no one pays attention in between outbreaks, except in places like Singapore, where there is very good surveillance," Ehrenberg said.

In Singapore, health workers aggressively control breeding sites by regularly spraying pesticides in parks and gardens. Government inspectors fine people for allowing water to build up in flower pots which is a favourite breeding site.

Singapore reported 14,000 dengue cases in 2005, but that fell to 3,597 cases in the first half of 2007, according to the WHO.

With 42,456 cases in 2006 and 45,893 in 2005, Thailand figures near the top of the dengue list. Fanned out across the country are 500,000 volunteers who educate villagers on mosquito control, chiefly by removing stagnant pools of water.